Volume 7, Issue 1 (6-2024)
Mod Med Lab J 2024, 7(1): 31-39 |
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Takhiri F, Keshavarz Alikhani H, Hassan M, Vosough M. MircroRNAs in Innate Immunity; The Smart Regulatory Network. Mod Med Lab J 2024; 7 (1) :31-39
URL: http://modernmedlab.com/article-1-151-en.html
URL: http://modernmedlab.com/article-1-151-en.html
Abstract: (321 Views)
MicroRNAs are regulatory elements at the post-transcriptional level that play a crucial role in all cellular and developmental processes. Numerous studies have demonstrated the substantial role of miRNAs in the development of immune cells, initiation of Toll-like receptors (TLRs) signaling, and production of cytokines in response to damaged-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs). MiRNAs contribute to development and regulation of immune system and inflammatory processes by regulating the expression of specific genes. Cancer and autoimmune diseases can arise due to dysregulated expression of some miRNAs involved in innate immune processes. In this review, the key miRNAs influencing immune system response and inflammatory processes and their role in development of immune cells are discussed.
Type of Study: Review Article |
Subject:
Immunology
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