en روش های تشخیص آزمایشگاهی Laboratory Methods مقاله پژوهشی Original Research Article <p dir="ltr" style="text-align: justify"><strong>Background and Objective:</strong> Beta-2 Microglobulin (&beta;2M) is a middle molecular weight uremic toxin. Lack of &beta;2M removal leads to &beta;2M accumulation and amyloidosis in hemodialysis patients. The present research aims to determine the relationship between &beta;2M and inflammatory factors, such as C-reactive protein (CRP), albumin, and high-density lipoprotein (HDL) in hemodialysis patients.&nbsp;</p> <p dir="ltr" style="text-align: justify"><strong>Methods:</strong> Fifty-four hemodialysis patients were selected and their pre- and post-dialysis serum levels of &beta;2M, CRP, albumin, and HDL, were measured.</p> <p dir="ltr" style="text-align: justify"><strong>Results:</strong> There was an obvious inverse relationship between &beta;2M level and serum level of albumin, while no relationship was found between &beta;2M and CRP or HDL.</p> <p dir="ltr" style="text-align: justify"><strong>Conclusion:</strong> According to the findings of this study, it was identified that inflammatory-induced increase in &beta;2M level in dialysis patients leads to reduced serum albumin</p> <p dir="ltr" style="text-align: justify"></p> Beta-2 Microglobulin, albumin, hemodialysis, inflammation. 17 22 http://modernmedlab.com/browse.php?a_code=A-10-1-18&slc_lang=en&sid=1 Mohammadreza Abdollahzadeh Estakhri 10031947532846001558 10031947532846001558 Yes Sina Hospital, Tehran University of Medical Science, Tehran, Iran. Parviz Kavakeb 10031947532846001559 10031947532846001559 No Sina Hospital, Tehran University of Medical Science, Tehran, Iran. Delaram Fathi 10031947532846001560 10031947532846001560 No Department of Technical and Vocational Organization, Karaj University, Karaj, Iran Gholamreza Karimi 10031947532846001561 10031947532846001561 No Faculty of Pharmacy, Mashhad University of Medical Science, Mashhad, Iran Amirhosein Mohammadpour 10031947532846001562 10031947532846001562 No Faculty of Pharmacy, Mashhad University of Medical Science, Mashhad, Iran Maryam Rahbar 10031947532846001563 10031947532846001563 No Sina Hospital, Tehran University of Medical Science, Tehran, Iran.