en ایمنی شناسی Immunology مقاله مروری Review Article <span style="font-size:11pt"><span style="line-height:150%"><span sans-serif="" style="font-family:Calibri,"><span style="font-size:13.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">MicroRNAs are regulatory elements at the post-transcriptional level that play a</span></span></span> <span style="font-size:13.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">crucial role in all cellular and developmental processes. Numerous studies have demonstrated the substantial role of miRNAs in the development of immune cells, initiation of Toll-like receptors (TLRs) signaling, and production of cytokines in response to damaged-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs). MiRNAs contribute to development and regulation of immune system and inflammatory processes by regulating the expression of specific genes. Cancer and autoimmune diseases can arise due to dysregulated expression of some miRNAs involved in innate immune processes. In this review, the key miRNAs influencing</span></span></span> <span style="font-size:13.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">immune system response and inflammatory processes and their role in development of immune cells are discussed.</span></span></span><span style="font-size:14.0pt"><span style="line-height:150%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span><br> &nbsp; ,MicroRNAs,Innate Immunity,Inflammatory processes,Immune cells 31 39 http://modernmedlab.com/browse.php?a_code=A-10-73-20&slc_lang=en&sid=1 Fereshteh Takhiri fereshtehtakhiri@gmail.com 10031947532846002261 10031947532846002261 No Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran Hani Keshavarz Alikhani hani.keshavarz865@gmail.com 10031947532846002262 10031947532846002262 No Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran Moustapha Hassan moustapha.hassan@ki.se 10031947532846002263 10031947532846002263 No Experimental Cancer Medicine, Institution for Laboratory Medicine, Karolinska Institute, Stockholm, Sweden Massoud Vosough masvos@yahoo.com 10031947532846002264 10031947532846002264 Yes Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran