en روش های تشخیص آزمایشگاهی Laboratory Methods مقاله پژوهشی Original Research Article <span style="font-size:11pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><b><span style="font-size:10.0pt">Background and Objective:</span></b><span style="font-size:10.0pt"> The measurement of the coefficient of variation (CV%) and bias has been used to check the precision and accuracy of laboratory-generated data. Indices like the capability index (Cp and Cpk) and the quality goal index ratio (QGI) take into account both CV and bias in order to categorize the results of various parameters, allowing for necessary actions to improve the outcomes of poorly performing parameters.</span></span></span><br> <span style="font-size:11pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><b><span style="font-size:10.0pt">Materials and Methods:</span></b><span style="font-size:10.0pt"> This is a retrospective study, and data required for the study were extracted between January 2024 and June 2024 from a tertiary care government hospital in Delhi. The Cp, Cpk, and QGI were calculated, and six-month averages of these indices were taken to categorize the parameters.</span></span></span><br> <span style="font-size:11pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><b><span style="font-size:10.0pt">Results:</span></b><span style="font-size:10.0pt"> For level 1 of internal quality control (IQC), the Cp indicated that sodium, chloride, urea, and low-density lipoprotein (LDL) performed marginally well, while potassium performed poorly. Meanwhile, the Cpk showed poor performance for sodium, potassium, chloride, urea, LDL, amylase, and lactate dehydrogenase (LDH). Sodium, potassium, chloride, urea, and creatinine had a QGI of <0.8, indicating that the bias was due to imprecision, while LDL had a QGI of >1.2, indicating that the bias was due to inaccuracy. For level 2 of IQC, Cp showed that sodium, chloride, LDH, and LDL were in the marginal range, and potassium performed poorly, while Cpk indicated poor performance for sodium, potassium, chloride, urea, protein, LDL, and LDH. Sodium, potassium, chloride, urea, and protein had a QGI of <0.8, indicating that the bias was due to imprecision, while the QGI of LDL was between 0.8 and 1.2, indicating that the bias was due to both inaccuracy and imprecision.</span></span></span><br> <span style="font-size:11pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><b><span style="font-size:10.0pt">Conclusion:</span></b><span style="font-size:10.0pt"> This study shows that Cp, Cpk, and QGI can be used to assess the analytical performance of a clinical chemistry laboratory and to implement measures for improving quality assurance.</span></span></span> Biochemistry, Laboratory, Clinical, Bias 22 30 http://modernmedlab.com/browse.php?a_code=A-10-923-1&slc_lang=en&sid=1 Sumana Kundu sumana.kundu19@gmail.com 10031947532846002250 10031947532846002250 No Department of Biochemistry, Maulana Azad Medical College, New Delhi, India Abhisek Mishra abhisekmishraberhampur@gmail.com 10031947532846002251 10031947532846002251 No Department of Biochemistry, Maulana Azad Medical College, New Delhi, India Kajal Nandi kajalnandi03@gmail.com 10031947532846002252 10031947532846002252 No Department of Biochemistry, Maulana Azad Medical College, New Delhi, India Binita Goswami binita.dr@gmail.com 10031947532846002253 10031947532846002253 Yes Department of Biochemistry, Maulana Azad Medical College, New Delhi, India