en علوم پزشکی Medical Sciences مقاله مروری Review Article <span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Coronavirus disease 2019 (COVID-19) is more common in patients with multiple sclerosis because of receiving immunosuppressive or immunomodulating disease-modifying therapies (DMTs). On the other hand, some of these drugs may interact on COVID-19 vaccines. In this commentary, first we introduce some available COVID-19 vaccines and then discuss the effect of different DMTs on immune responses after vaccination. We have not found a connection between vaccination and MS relapses, so we suggest that the benefit from the vaccine outweighs any potential risks in these patients.</span></span> Coronavirus disease 2019 (COVID-19), Multiple sclerosis, Vaccination, Disease-modifying therapies (DMTs) 29 37 http://modernmedlab.com/browse.php?a_code=A-10-73-12&slc_lang=en&sid=1 Seyed Massood Nabavi seyedmassoodnabavi@gmail.com 10031947532846001987 10031947532846001987 Yes Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. Mehrnoosh Mehrabani mehrnooshmehrabani@yahoo.com 10031947532846001988 10031947532846001988 No Arya group for treatment and research in multiple sclerosis, Tehran, Iran. Shahedeh Karimi karimi58shah@gmail.com 10031947532846001989 10031947532846001989 No Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. Ehsan Mohammadianinejad ehsanneuro@gmail.com 10031947532846001990 10031947532846001990 No Iranian center of neurological research, neuroscience institute, Tehran University of medical sciences, Tehran, Iran Mehran Ghafari m.ghaffari@sbmu.ac.ir 10031947532846001991 10031947532846001991 No Neurology department, Shahid Beheshti University of medical sciences, Tehran, Iran. Maryam Dastoorpoor mdastoorpour@yahoo.com 10031947532846001992 10031947532846001992 No Epidemiology and public health department, Jondishapour University of medical sciences, Ahvaz, Iran.