Modern Medical Laboratory Journal
Mod Med Lab J
Medical Sciences
http://modernmedlab.com
1
admin
2371-770X
2371-770X
10.30699/mmlj17
en
jalali
1400
8
1
gregorian
2021
11
1
4
2
online
1
fulltext
en
Comparison of two automated methods for the measurement of glycated hemoglobin HBA1C: ADAMS A1c (ARKRAY) versus Capillarys 2 Flex Piercing® (SEBIA)
روش های تشخیص آزمایشگاهی
Laboratory Methods
مقاله کوتاه پژوهشی
Brief Original Article
Introduction: The aim of this work is to present the results of a comparative study between the determination of glycated hemoglobin (HBA1C) on the ADAMS A1c® (ARKRAY) and Capillarys 2 Flex Piercing® (SEBIA).<br>
Materials and methods: 310 venous blood samples were randomly selected from routine HBA1C tests. The HBA1C assay was performed on ADAMS A1c® (ARKRAY) and Capillarys 2 Flex Piercing® (SEBIA) during the same day. The data obtained were analyzed by the statistical software MedCalc Version 15.1.0.<br>
Results: The results obtained show a good correlation between the 2 methods: the equation of the Passing-Bablok line is of type Y (Capillarys 2 Flex Piercing®) = -0.550 + 1.119 X (ADAMS A1c) the 95% confidence interval of this slope is -0.6467 to - 0.4414 with r = 0.982 and p <0.0001. The Bland-Altman plot shows that the average bias between the two methods is in the order of 0.3 and that the difference between the Capillarys and HPLC measurements of Hba1c is in the range of +1.96 to -1.96 and the Deming regression equation Y (Capillarys 2 Flex Piercing®) = -0.3388 + 1.0911 X (ADAMS A1c).<br>
Conclusion: Our study shows a good agreement of HBA1C results between the Capillarys 2 Flex Piercing® (SEBIA) and ADAMS A1c® (ARKRAY). Laboratory work requires professionals to take into account variations in results when changing methods in their routine work by comparing their results on the various methods.
Glycatedhaemoglobin,Assay,Comparison,ADAMSA1c®(ARKRAY),Capillarys2FlexPiercing®(SEBIA)
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39
http://modernmedlab.com/browse.php?a_code=A-10-55-4&slc_lang=en&sid=1
Noussaiba
Benhamza
noussaiba.ben@gmail.com
10031947532846001760
10031947532846001760
No
Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda, Morocco.
El-houcine
Sebbar
e.sebbar@ump.ac.ma
10031947532846001761
10031947532846001761
Yes
Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda, Morocco.
Adnane
Naili
adnanenaili90@gmail.com
10031947532846001762
10031947532846001762
No
Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda, Morocco.
Mohammed
Choukri
mohammedchoukri801@gmail.com
10031947532846001763
10031947532846001763
No
Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda, Morocco.