http://modernmedlab.com en-us Copyright 2005, Academic Web Tools modernmedlab@gmail.com () modernmedlab@gmail.com () Mon, 21 Oct 2024 08:26:00 +0330 Mon, 21 Oct 2024 08:26:00 +0330 Yektaweb Collection - https://yektaweb.com http://modernmedlab.com/files/site1/site/logo.gif http://modernmedlab.com/index.php?sid=1 http://modernmedlab.com/content/209/ Breast cancer is the most common cancer globally with around 2.3 million new cases every year. It represents one in eight cancer cases in both sexes and a quarter of all cancers in women1 with 70% mortality occurring in resource constrained settings. Health system barriers and patient level factors with low levels of awareness and knowledge are contributing to low uptake of early detection services, with resultant late-stage diagnoses and poor outcomes. In many resource-constrained settings, breast cancer affects a relatively younger population significantly contributing to premature mortality and maternal orphans. http://modernmedlab.com/find.php?item=1.15.209.en Mon, 21 Oct 2024 08:26:00 +0330 http://modernmedlab.com/find.php?item=1.15.209.en Journal News http://modernmedlab.com/content/208/ Liver cancer awareness is essential for improving early detection, treatment, and prevention. Here are some key aspects to consider for promoting liver cancer awareness: 1. Education on Risk Factors Factors that increase the risk of primary liver cancer include: Chronic infection with HBV or HCV. Chronic infection with the hepatitis B virus (HBV) or hepatitis C virus (HCV) increases your risk of liver cancer. Cirrhosis. This progressive and irreversible condition causes scar tissue to form in your liver and increases your chances of developing liver cancer. http://modernmedlab.com/find.php?item=1.15.208.en Sun, 06 Oct 2024 10:53:00 +0330 http://modernmedlab.com/find.php?item=1.15.208.en Journal News http://modernmedlab.com/content/207/ Histotripsy is an innovative medical technique that utilizes focused ultrasound to generate high-pressure acoustic waves that create cavitation bubbles in tissues, leading to localized tissue disruption. This method has garnered interest in cancer treatment due to several potential advantages: Non-Invasiveness: Histotripsy is a non-invasive method, which means it can treat tumors without the need for surgical intervention, reducing recovery times and associated complications. Targeted Treatment: The focused nature of ultrasound allows for precise targeting of tumor tissues while sparing surrounding healthy tissues, potentially minimizing collateral damage and side effects. http://modernmedlab.com/find.php?item=1.15.207.en Mon, 30 Sep 2024 10:58:00 +0330 http://modernmedlab.com/find.php?item=1.15.207.en Journal News http://modernmedlab.com/content/206/ A large prospective study utilizing data from the UK Biobank investigated the relationship between caffeine, coffee, and tea consumption and the onset of cardiometabolic diseases (CM) in 360,406 participants. The study revealed nonlinear inverse associations, indicating that moderate coffee consumption (three cups per day) and caffeine intake (200-300 mg daily) significantly lowered the risk of developing CM compared to nonconsumers or those consuming less than 100 mg of caffeine daily, with hazard ratios of 0.519 and 0.593, respectively. Additionally, advanced multistate models demonstrated that moderate caffeine intake is associated with reduced risks throughout various stages of CM development, highlighting its potential protective effects against transitioning from a disease-free state to the onset of CM. http://modernmedlab.com/find.php?item=1.15.206.en Mon, 23 Sep 2024 13:26:00 +0330 http://modernmedlab.com/find.php?item=1.15.206.en Journal News http://modernmedlab.com/content/205/ Results from the Phase I trial the first human study of this therapy were presented on Saturday, September 14th, at the European Society of Medical Oncology conference in Barcelona by the UK Chief Investigator from the School of Cancer & Pharmaceutical Sciences and Guy s and St Thomas NHS Foundation Trust. The trial is sponsored by Moderna. This mRNA immunotherapy is part of a broader trend of cancer vaccines entering clinical trials globally. The therapy functions by presenting common tumor markers to the patients immune systems, helping them recognize and attack cancer cells that express these markers, while potentially eliminating cells that could suppress the immune response. http://modernmedlab.com/find.php?item=1.15.205.en Tue, 17 Sep 2024 14:05:00 +0330 http://modernmedlab.com/find.php?item=1.15.205.en Journal News http://modernmedlab.com/content/204/ Suicide represents a significant public health issue, claiming over 700,000 lives each year across the globe. The impact of each suicide extends beyond the individual, resulting in profound social, emotional, and economic repercussions that resonate within families and communities everywhere. World Suicide Prevention Day, observed annually on September 10, serves as a crucial reminder of the ongoing global effort to address the complexities surrounding suicide. The triennial theme for 2024-2026, "Changing the Narrative on Suicide," emphasizes the urgent need to shift societal perceptions of this sensitive issue. http://modernmedlab.com/find.php?item=1.15.204.en Tue, 10 Sep 2024 13:13:00 +0330 http://modernmedlab.com/find.php?item=1.15.204.en Journal News http://modernmedlab.com/content/203/ Ahead of World Cancer Day, the International Agency for Research on Cancer (IARC), the cancer agency of the World Health Organization (WHO), unveiled the most recent global cancer burden estimates. Additionally, WHO shared findings from a survey conducted in 115 countries, revealing that a significant number of nations do not adequately fund essential cancer and palliative care services as part of universal health coverage (UHC). The IARC estimates, based on the best sources of data available in countries in 2022, highlight the growing burden of cancer, the disproportionate impact on underserved populations, and the urgent need to address cancer inequities worldwide. http://modernmedlab.com/find.php?item=1.15.203.en Sun, 04 Feb 2024 10:26:00 +0330 http://modernmedlab.com/find.php?item=1.15.203.en Journal News http://modernmedlab.com/content/202/ Clustered Regularly Interspaced Short Palindromic Repeats, commonly known as CRISPR, has emerged as a groundbreaking gene-editing technology, revolutionizing the field of molecular biology. Originally discovered as part of the bacterial immune system, CRISPR has been adapted for precise manipulation of DNA sequences in various organisms, offering unprecedented opportunities in medicine, agriculture, and biotechnology. CRISPR was initially identified in bacteria as a defense mechanism against viral infections. The system consists of short, partially palindromic repeated DNA sequences interspersed with unique spacer sequences derived from past viral invasions. http://modernmedlab.com/find.php?item=1.15.202.en Sat, 20 Jan 2024 14:15:00 +0330 http://modernmedlab.com/find.php?item=1.15.202.en Journal News http://modernmedlab.com/content/201/ Cervical cancer develops in a woman's cervix (the entrance to the uterus from the vagina). Almost all cervical cancer cases (99%) are linked to infection with high risk human papillomavirus (HPV), an extremely common virus transmitted through sexual contact. Although most infections with HPV resolve spontaneously and cause no symptoms, persistent infection can cause cervical cancer in women. Cervical cancer is the 6th most common cancer in women in the Eastern Mediterranean Region. In 2020, an estimated 89,800 women were diagnosed with cervical cancer in the Region and more than 47,500 women died from the disease. http://modernmedlab.com/find.php?item=1.15.201.en Tue, 09 Jan 2024 14:55:00 +0330 http://modernmedlab.com/find.php?item=1.15.201.en Journal News http://modernmedlab.com/content/200/ Smoking is a major cause of cardiovascular disease (CVD) and causes approximately one of every four deaths from CVD. According to World Health Organization data, smoking determines 10% of all CVDs. Tobacco smoking usage causes approximately 6 million death per year throughout the world, in the United States almost 500,000 deaths can be attributed to smoking and about 10% of these deaths are caused from second-hand smoke exposure. Epidemiologic studies have supported the assumption that cigarette smoking increases the incidence of myocardial infarction and fatal coronary artery diseases. http://modernmedlab.com/find.php?item=1.15.200.en Tue, 19 Dec 2023 17:39:00 +0330 http://modernmedlab.com/find.php?item=1.15.200.en Journal News http://modernmedlab.com/content/199/ The human gut microbiome impacts human brain health in numerous ways: (1) Structural bacterial components such as lipopolysaccharides provide low-grade tonic stimulation of the innate immune system. Excessive stimulation due to bacterial dysbiosis, small intestinal bacterial overgrowth, or increased intestinal permeability may produce systemic and/or central nervous system inflammation. (2) Bacterial proteins may cross-react with human antigens to stimulate dysfunctional responses of the adaptive immune system. (3) Bacterial enzymes may produce neurotoxic metabolites such as D-lactic acid and ammonia. http://modernmedlab.com/find.php?item=1.15.199.en Tue, 05 Dec 2023 15:15:00 +0330 http://modernmedlab.com/find.php?item=1.15.199.en Journal News http://modernmedlab.com/content/198/ Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the disease. The new medicine, Casgevy, works by targeting the problematic gene in a patient's bone marrow stem cells so that the body can make properly functioning hemoglobin. Patients first receive a course of chemotherapy to make space for the new cells. Then, doctors take stem cells from the patient's bone marrow and use genetic editing techniques in a laboratory to fix the gene. http://modernmedlab.com/find.php?item=1.15.198.en Wed, 29 Nov 2023 11:16:00 +0330 http://modernmedlab.com/find.php?item=1.15.198.en Journal News http://modernmedlab.com/content/197/ Gene transcription, a pivotal process in molecular biology, is a highly regulated and intricate mechanism that enables the expression of genetic information. It commences as RNA polymerase recognizes and binds to a specific promoter region on DNA, initiating the unwinding of the DNA double helix. Subsequently, the enzyme synthesizes a complementary RNA strand using ribonucleotides along the template DNA strand. This process elongates the RNA molecule, which may undergo post-transcriptional modifications to become mature RNA, including mRNA, rRNA, and tRNA. http://modernmedlab.com/find.php?item=1.15.197.en Tue, 07 Nov 2023 11:07:00 +0330 http://modernmedlab.com/find.php?item=1.15.197.en Journal News http://modernmedlab.com/content/196/ The immune system is a complex network of cells with critical functions in health and disease. However, a comprehensive census of the cells comprising the immune system is lacking. In a recent study, the researchers estimated the abundance of the primary immune cell types throughout all tissues in the human body. They conducted a literature survey and integrated data from multiplexed imaging and methylome-based deconvolution. They also considered cellular mass to determine the distribution of immune cells in terms of both number and total mass. Their results indicate that the immune system of a reference 73 kg man consists of 1. http://modernmedlab.com/find.php?item=1.15.196.en Tue, 31 Oct 2023 14:13:00 +0330 http://modernmedlab.com/find.php?item=1.15.196.en Journal News http://modernmedlab.com/content/195/ Researchers in Sweden have developed a 3D-printed, microscale implant in the eye to offer cell-based therapy that could treat diabetes. The researchers chose pancreatic islets, cell clusters in the pancreas that produce insulin, as donors cells have been used in experimental treatments for type 1 diabetes. Anna Herland, senior lecturer in the Division of Bionanotechnology at SciLifeLab at KTH and the AIMES research center at KTH and Karolinska Institutet, says that the eye is ideal for this technology because it has no immune cells that react unfavorably in the first stage of implantation. http://modernmedlab.com/find.php?item=1.15.195.en Tue, 24 Oct 2023 14:18:00 +0330 http://modernmedlab.com/find.php?item=1.15.195.en Journal News